Study of inhibitory effects of some traditional medicine formulations on adrenaline-induced hyperglycaemia in animal models

ABSTRACT

Traditional medicine formulations TMF-27, TMF-28 and TMF-32 have been used traditionally to treat diabetes in Myanmar. Blood Glucose levels of adrenaline-induced diabetic rabbits were determined after oral administration of maximum dose of the traditional medicine formulations TMF-27 TMF-28 and TMF-32 and their watey extracts respectively. From the data obtained, it was concluded that the oral administration of 1.6 g/kg TMFs did not produce inhibition of hypergly-caemic effect in rabbits. Only the water soluble extract of TMF-32 inhibited the hyperglycaemic blood glucose level on adrenaline-diabetic rabbits (p<0.05) ans rats (p<0.05).