Cytogenetic analysis of Down syndrome in Gujarat.
Indian Pediatr
;
2007 Oct; 44(10): 774-7
Article
in English
| IMSEAR
| ID: sea-12769
ABSTRACT
During 1995 to 2006, 382 cases clinically suspected for Down syndrome were investigated for cytogenetic study. Free trisomy 21 constituted 84.8% of cases, translocation 8.9%, mosaic 3.9% and in 2.4% cases regular T21 was associated with structural or numerical changes. Translocation was parentally inherited in 26.5% cases and maternal transmission was twice as common as paternal. Males were more pronounced to be affected than females in all the groups. 91.6% of DS babies were born to younger mothers (20-35 yr) compared to 8.4% in elderly mothers (>35 yr).
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Female
/
Humans
/
Male
/
Infant, Newborn
/
Child
/
Child, Preschool
/
Adolescent
/
Maternal Age
/
Down Syndrome
/
Adult
Country/Region as subject:
Asia
Language:
English
Journal:
Indian Pediatr
Year:
2007
Type:
Article
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