Sydenham's chorea.
Indian Pediatr
;
1996 Feb; 33(2): 112-5
Article
in English
| IMSEAR
| ID: sea-12909
ABSTRACT
OBJECTIVE:
To study the clinical profile in patients with Sydenham's chorea.DESIGN:
Prospective.SETTING:
Medical college and hospital.SUBJECTS:
Sixty cases with Sydenham's chorea, between 1988 and 1994, were studied. Of these 36 were girls; the mean age at presentation was 11.1 yr (range 7-16 yr).RESULTS:
Female predominance was apparent only after 9 years of age. There was a high familial incidence for both chorea and rheumatic fever. Generalized chorea was seen in 40 and hemichorea in 20 patients. The chorea lasted from 5 to 40 days; 13 patients had recurrent episodes. Gait disturbances, dysarthria and weakness were common. Six patients had co-existing heart disease, 4 had arthritis and one had subcutaneous nodules. A raised ESR and positive ASO titer were seen in 37 and 20 patients respectively.CONCLUSIONS:
There was an increased incidence of Sydenham's chorea after 9 years of age in girls possibly suggesting the influence of female sex hormones. A high incidence of neurologic manifestations were noted. Acute phase reactants were raised in almost half the patients. Sodium valproate, whenever used, was effective in controlling the chorea.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prognosis
/
Rheumatic Fever
/
Female
/
Humans
/
Male
/
Child
/
Incidence
/
Prospective Studies
/
Chorea
/
Adolescent
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Country/Region as subject:
Asia
Language:
English
Journal:
Indian Pediatr
Year:
1996
Type:
Article
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