Mid-dilution on-line hemodiafiltration: technology and efficiency outcome

ABSTRACT

Background: The standard pre- and post-dilution methods of fluid substitution in on-line hemodiafiltration (OL-HDF) have limitations in removal of uremic toxins. Objective: To review the technique and efficiency outcomes of mid-dilution OL-HDF. Results: Mid-dilution OL-HDF could provide comparable or better efficiency with pre- and post-dilution modes. There are no serious adverse effects or technical complications. Conclusion: It appears that mid-dilution OL-HDF could combine the advantages and overcome the disadvantages of pre- and post-dilution modes.