Viral pathogens of acute lower respiratory tract infection in China.
Indian Pediatr
;
2008 Dec; 45(12): 971-5
Article
in English
| IMSEAR
| ID: sea-13301
ABSTRACT
OBJECTIVES:
To document the viral etiology of acute lower respiratory tract infection (ALRIs) in Chinese children.SETTING:
Children Hospital, Zhejiang University, China. STUDYDESIGN:
Cross-sectional.PARTICIPANTS:
34885 children with ALRI between January 2001 to December 2006.METHODS:
Nasopharyngeal aspirates were collected from all subjects. Respiratory syncytial virus (RSV), adenovirus (ADV), type 1 to 3 parainfluenza viruses (PIV), and type A and B influenza virus (Flu) were detected by direct immunofluorescence.RESULTS:
Viruses were identified in 32.3% cases, including RSV (23.6%), PIV 3 (4.3%), Flu A (2.0%), ADV (1.7%), PIV I (0.6%), Flu B (0.2%) and PIV 2 (0.1%). RSV and PIV 3 predominated in younger children while Flu A and Flu B predominated in older children (P<0.001, respectively). PIV 1 was more prevalent in children aged 1 to 3 years. The peak frequency of RSV, PIV 3 and Flu A were in early spring, June to August, and August and September, respectively. Flu B had a peak in the winter and spring. Adenovirus infections occurred in all seasons with a relatively constant frequency.CONCLUSIONS:
Viruses are an important cause of ALRIs in Chinese children constituting 1/3 of total cases. RSV is the most common pathogen.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Respiratory Tract Infections
/
Female
/
Humans
/
Male
/
Adenoviridae
/
Child, Preschool
/
China
/
Acute Disease
/
Respiratory Syncytial Virus, Human
/
Parainfluenza Virus 1, Human
Country/Region as subject:
Asia
Language:
English
Journal:
Indian Pediatr
Year:
2008
Type:
Article
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