A Randomized Controlled Trial Comparing 2-Octylcyanoacrylate and Absorbable Subcuticular Suture in Small Surgical Incision Wound Closure

ABSTRACT

Abstract A Randomized Controlled Trial Comparing 2-Octylcyanoacrylate and Absorbable Subcuticular Suture in Small Surgical Incision Wound Closure Suphakan  Techapongsatorn MD, MSc (Clinical Epidemiology), FICS Department of Surgery, BMA Medical College and Vajira Hospital Objective: To compare the efficacy of 2-octylcyanoacrylate with absorbable subcuticular suture for surgical incision wound closure. Study design: Randomized controlled trial. Subjects: A total of 88 patients, who were indicated for surgical removal of benign skin or subcutaneous lesions in the Department of Surgery, BMA Medical College and Vajira Hospital during March and July 2007 were enrolled. Methods: All patients were randomly assigned into two groups 2-octylcyanoacrylate for wound closure (n= 44) and absorbable subcuticular suture for wound closure (n=44). The closure wound was evaluated on day 7 postoperatively. Main outcome measures: Wound closure evaluation score. Results: The wound closure evaluation score in the 2-octylcyanoacrylate group was statistically significant better than absorbable subcuticular suture group, particularly in terms of wound approximation, wound inflammation and wound epithelization. Conclusion: 2-octylcyanoacrylate has higher wound closure evaluation score than absorbable subcuticular suture for closure of small surgical incision wound. Vajira Med J 2008 ; 52 93 - 100