Myocardial ischemia induced by nebulized fenoterol for severe childhood asthma.
Indian Pediatr
;
2005 Oct; 42(10): 1013-8
Article
in English
| IMSEAR
| ID: sea-13475
ABSTRACT
We examined for myocardial ischemia induced by continuous inhalation of fenoterol in children with severe acute asthma. Thirty children with severe acute asthma were evaluated for signs of myocardial ischemia when treated with 0.5 mg kg dose (maximum 15 mg) of inhaled fenoterol for one hour. The heart rate was measured before and after inhalation. Cardiac enzymes (creatine kinase, creatine kinase MB fraction and troponin levels) were measured at admission and 12 hours later. An EKG was recorded before inhalation was started and immediately after its completion to detect the presence of any evidence of myocardial ischemia. All patients developed significant increase in heart rate. Six patients showed EKG changes compatible with myocardial ischemia, despite normal enzyme levels. Patients with severe acute asthma show tachycardia and may show EKG changes of myocardial ischemia.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Asthma
/
Administration, Inhalation
/
Bronchodilator Agents
/
Female
/
Humans
/
Male
/
Child
/
Child, Preschool
/
Myocardial Ischemia
/
Statistics, Nonparametric
Language:
English
Journal:
Indian Pediatr
Year:
2005
Type:
Article
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