Effect of alcohol on carbohydrate metabolic profiles in rat kidney: A study with reference to aging.

ABSTRACT

This study was conducted to know the influence of alcohol and aging on carbohydrate metabolic profiles in the kidney tissue of control and experimental male albino rats. Alcohol significantly decreased the levels of glucose, total proteins, total carbohydrates and increased free amino acids, pyruvate and lactate in the kidney tissue of both age groups of rats. Aging induced the elevation of the levels of glucose, total carbohydrates, free amino acids and lactate, while it decreased the total protein and pyruvate contents. This suggests rapid utilisation of carbohydrates and degradation of proteins to meet energy demands under alcoholic stress. Thus more alterations were observed in the carbohydrate metabolic profiles in kidney of both age groups of experimental rats.