Pathophysiology & genetics of obstructive sleep apnoea.
Article
in English
| IMSEAR
| ID: sea-135427
ABSTRACT
Obstructive sleep apnoea (OSA) is a highly prevalent condition with proven neurocognitive and cardiovascular consequences. OSA patients experience repetitive narrowing or collapse of the pharyngeal airway during sleep. Multiple factors likely underlie the pathophysiology of this condition with considerable inter-individual variation. Important risk factors for OSA include obesity, male gender, and ageing. However, the mechanisms underlying these major risk factors are not well understood. We briefly review the state-of-the-art knowledge regarding OSA pathogenesis in adults and highlight the potential role of genetics in influencing key OSA pathophysiological traits.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Respiration
/
Respiratory System
/
Sleep
/
Time Factors
/
Biomechanical Phenomena
/
Humans
/
Cardiovascular Diseases
/
Risk Factors
/
Sleep Apnea, Obstructive
/
Lung
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Language:
English
Year:
2010
Type:
Article
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