Salmeterol vs. formoterol: a comparison of rapid bronchodilator effect in a randomized controlled trial.
Indian Pediatr
;
2008 Mar; 45(3): 225-8
Article
in English
| IMSEAR
| ID: sea-13544
ABSTRACT
We conducted this double blind randomized controlled trial to compare the rapid bronchodilator effect of salmeterol and formoterol in 60 children with stable asthma. Participants were randomized to receive either salmeterol (50 microg) (n=31) or formoterol (24 microg) (n=29) by metered dose inhaler and spacer. Spirometry was performed at baseline, at 30 minutes, and at 60 minutes. Bronchodilatation was assessed by changes in FEV(1) at 30 and 60 minutes. Baseline parameters were comparable in the two groups. There was no significant difference in the FEV(1) at 30 and 60 minutes between two groups. We conclude that salmeterol and formoterol both cause bronchodilator response at end of 60 minutes and are not different with regards to their rapid bronchodilator response.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Asthma
/
Spirometry
/
Bronchodilator Agents
/
Female
/
Humans
/
Male
/
Child
/
Peak Expiratory Flow Rate
/
Forced Expiratory Volume
/
Double-Blind Method
Type of study:
Controlled clinical trial
Language:
English
Journal:
Indian Pediatr
Year:
2008
Type:
Article
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