An allele specific PCR assay for screening for drug resistance among Wuchereria bancrofti populations in India.

Hoti, S L; Dhamodharan, R; Subramaniyan, K; Das, P K

Hoti, S L; Dhamodharan, R; Subramaniyan, K; Das, P K.

Article in En | IMSEAR | ID: sea-135884

Subject(s)

Albendazole/pharmacology; Albendazole/therapeutic use; Alleles; Amino Acid Sequence; Animals; Base Sequence; Drug Resistance/genetics; Elephantiasis, Filarial/drug therapy; Elephantiasis, Filarial/parasitology; Filaricides/pharmacology; Filaricides/therapeutic use; Humans; Molecular Sequence Data; Parasitic Sensitivity Tests; Polymerase Chain Reaction/methods; Polymorphism, Genetic; Sequence Alignment; Tubulin/genetics; Wuchereria bancrofti/drug effects; Wuchereria bancrofti/genetics; Wuchereria bancrofti/physiology

Key words

Albendazole; anthelmintic resistance; benzimidazole; b-tubulin; Wuchereria bancrofti

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Full text: 1 Index: IMSEAR Main subject: Polymorphism, Genetic / Tubulin / Wuchereria bancrofti / Elephantiasis, Filarial / Humans / Drug Resistance / Molecular Sequence Data / Base Sequence / Albendazole / Polymerase Chain Reaction Type of study: Diagnostic_studies / Screening_studies Language: En Year: 2009 Type: Article

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