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Evaluation of alternative diagnostic techniques for diagnosis of cerebral malaria in a tertiary referral hospital in Bangladesh.
Article in English | IMSEAR | ID: sea-1359
ABSTRACT
Five alternative techniques for diagnosis of malaria were evaluated in 124 clinically diagnosed cerebral malaria cases admitted in a tertiary hospital in Bangladesh. Clinical diagnosis of cerebral malaria was done by WHO criteria. The tests were conventional routine malaria microscopy; prolonged microscopy; dipstick antigen capture assay (Para Sight TM-F test); pigments in peripheral leucocytes and routine microscopy repeated at 12 hours interval. First four tests were done at 0 hours of hospital admission and repeat routine microscopy was added at 12 hours interval. Diagnostic capability of the test was 64%, 65%, 69%, 27% and 63% respectively. None of the tests except pigments in peripheral leucocytes was superior at initial evaluation. Only the dipstick test added 5% more diagnostic possibility compared with routine microscopy as standard. Stratification of diagnostic capability in different ways improved diagnosis 15% and 11% in smear negative cases by dipstick and prolonged microscopy respectively. It was increased by 50% (5/10 patients) with dipstick test in the smear negative patients with history of anti-malarials prior to hospital admission.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Plasmodium falciparum / Reagent Kits, Diagnostic / Bangladesh / Brain Diseases / Female / Humans / Male / Glasgow Coma Scale / Child / Risk Factors Type of study: Diagnostic study / Etiology study / Risk factors Country/Region as subject: Asia Language: English Year: 2008 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Plasmodium falciparum / Reagent Kits, Diagnostic / Bangladesh / Brain Diseases / Female / Humans / Male / Glasgow Coma Scale / Child / Risk Factors Type of study: Diagnostic study / Etiology study / Risk factors Country/Region as subject: Asia Language: English Year: 2008 Type: Article