Combination treatment of low fluence photodynamic therapy and intravitreal ranibizumab for choroidal neovascular membrane secondary to angioid streaks in Paget's disease – 12 month results.

Prabhu, Varsha V; Morris, Rodney J; Shah, Parag K; Narendran, V

Prabhu, Varsha V; Morris, Rodney J; Shah, Parag K; Narendran, V.

Indian J Ophthalmol ; 2011 July; 59(4): 306-308

Article in English | IMSEAR | ID: sea-136195

ABSTRACT

ABSTRACT

Angioid streaks also called Knapp striae are small breaks in the Bruch's membrane and have been reported with a host of systemic diseases. Rupture of streaks or development of secondary choroidal neovascular membrane (CNVM) carries a dismal visual prognosis. We report the successful treatment of CNVM secondary to Paget's disease using low fluence photodynamic therapy (PDT) and intravitreal ranibizumab.

Subject(s)

Angiogenesis Inhibitors/administration & dosage; Angioid Streaks/complications; Angioid Streaks/diagnosis; Angioid Streaks/etiology; Antibodies, Monoclonal/administration & dosage; Antibodies, Monoclonal, Humanized; Choroidal Neovascularization/diagnosis; Choroidal Neovascularization/drug therapy; Choroidal Neovascularization/etiology; Drug Therapy, Combination; Fluorescein Angiography; Fundus Oculi; Humans; Intravitreal Injections; Male; Middle Aged; Osteitis Deformans/complications; Osteitis Deformans/pathology; Photochemotherapy/methods; Treatment Outcome

Intravitreal ranibizumab; Paget's disease; subfoveal choroidal neovascular membrane

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Osteitis Deformans / Photochemotherapy / Humans / Male / Fluorescein Angiography / Treatment Outcome / Choroidal Neovascularization / Angiogenesis Inhibitors / Drug Therapy, Combination / Intravitreal Injections Type of study: Prognostic study Language: English Journal: Indian J Ophthalmol Year: 2011 Type: Article

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