Neuroprotection in glaucoma.
Indian J Ophthalmol
;
2011 Jan; 59 (Suppl1): 102-113
Article
in English
| IMSEAR
| ID: sea-136260
ABSTRACT
Glaucoma is a neurodegenerative disease characterized by loss of retinal ganglion cells and their axons. Recent evidence suggests that intraocular pressure (IOP) is only one of the many risk factors for this disease. Current treatment options for this disease have been limited to the reduction of IOP; however, it is clear now that the disease progression continues in many patients despite effective lowering of IOP. In the search for newer modalities in treating this disease, much data have emerged from experimental research the world over, suggesting various pathological processes involved in this disease and newer possible strategies to treat it. This review article looks into the current understanding of the pathophysiology of glaucoma, the importance of neuroprotection, the various possible pharmacological approaches for neuroprotection and evidence of current available medications.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Carbonic Anhydrase Inhibitors
/
Prostaglandins
/
Glaucoma
/
Clinical Trials as Topic
/
Administration, Topical
/
Neuroprotective Agents
/
Adrenergic Antagonists
/
Evidence-Based Medicine
/
Antihypertensive Agents
Type of study:
Risk factors
Language:
English
Journal:
Indian J Ophthalmol
Year:
2011
Type:
Article
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