Urine iodine inresligalion in Thailand.

ABSTRACT

The heating block method is a method for the routine determination of urine iodine that has been modified from the Program Against Micronutrient Malnutrition (PAMM) method. Normal values of adult urine iodine (age 35-70 years) in Bangkok were (mean + SD) 110.9+ 74.6 with a median values of 96.8 ตg/L (n = 66). Urine iodine values of adults from Maehongson and Petchabun were (mean + SD) 465.1+ 293.1 with a median value of 399.5 ตg/L (n=86), and 127.8+ 74.1 with a median value of 115.4 mg/L (n = 140), respectively. The mean and SD of the iodine content of urine from school children (age 7-12 years) in Uttraradit, Maehongson and Trang were 401.0+ 373.2 (n = 77), 1,171.1+ 1,078.4 (n = 97) and 275.0+ 399.4 (n = 46), and the median values were 264.5, 998.6 and 137.0 mg/L, respectively. There was no change in urine iodine concentration over three years despite storage a 37oC, 4 oC and 0 oC. We have participated in the PAMM-Centers for Disease Control and Prevention (CDC) Inter-Laboratory Urine Iodine Quality Assurance Program to fulfill quality assurance criteria in our testing. The results of three blind urine iodine levels were well correlated to consensus mean and %CV for inter assays were less than 15.