Venous thromboembolism and combined oral contraception in Thai women.

ABSTRACT

Hospital-based case-control study risk of venous thromboembolism (VTE) associated with combined oral contraceptives (OC) in Thai women aged 20-44 years was 7.6. Body mass index (BMI) of cases were significantly higher than controls. The risk of VTE in women having BMI more than 25 kg/m2 was 5.8. Cigarette smoking and alcoholic used did not the risk of VTE in OC user. The OC prevalence in this study in cases and controls were 39.5% and 7.9% respectively. All combined pills composed of 0.05 mg. Or less estrogen and second generation progestogen. This study suggested that the prescription of combined oral contraception to Thai overweight women should be avoided because it increased the risk of venous thromboembolism by two risk factors.