Relationship between cervical cone margins and residual lesions in subsequent hysterectomy.

ABSTRACT

A cross-sectional study was performed to assess the relationship between cervical conization specimens (pathological diagnosis of CIN III or MIC) and subsequent hysterectomy specimens from 140 patients at Siriraj Hospital. It was found that the pathological diagnosis of CIN III and MIC were related significantly to the lesions found at cervical cane margins (29.8% and 57.7% respectively, P < 0.01) but no relationship to the residual lesions in subsequent hysterectomy (P > 0.05). 98.9% of cone specimens with margin-free have been found absent of residual lesions in subsequent hysterectomy whereas 61.2% of involved margins have been present. Lestions at cervical cone margins were related significantly (P <0.01) to residual lesions in subsequent hysterectomy and could be an appropriate guideline in further management for patients undergone cervical conization.