All-in-one parenteral nutrition in surgical neonates.

ABSTRACT

During 1982-1990, we gave peripheral parenteral nutrition (PPN) using “single bottle technique” to 130 neonates with very satisfactory results. After following some experimental works from literature on lipid emulsion stability, we have developed total nutritional admixtures (all-in-one) that incorporate fat, aminoacids, dextrose, minerals, trace elements and vitamins in one container. Since 1993, all-in-one PN has been given to 27 neonates. The majority of cases suffered gastroschisis, omphalocele, tracheo-esophageal fistula, intestinal atresia and necrotizing enterocolitis. Duration of all-in=one feeding ranged from 5 to 46 days (60% were within 8-15 days). Complications ere minimal, phlebitis occurred only in 2 cases and cholestasis in one case. No precipitation or bacterial growth was detected. Five babies died from the severity of their conditions not from PPN. Compared with 51 neonates who received the old conventional method in the same period f time, there were no difference in the result. The all-in-one admixture ad administration of nutrition is simpler for the nurses, allowing more time for other activities and only one infusion pump is used. The cost of the conventional parenteral nutrition in the neonate is well tolerated, effective and safe.