Cortisol and 17-hydroxyprogesterone in saliva.

ABSTRACT

Radioimmunoassays of cortisol and 17OHP in saliva may replace the blood and urine measurements. The steroids in saliva obtained from normal subjects showed similar patterns of circadian rhythm, menstrual profiles and the responses to dynamic tests as seen in blood. The concentrations of these two salivary steroids measured here are similar to those previously reported and the advantages of salivary steroid measurements are suggested for routine clinical assessment of adrenocortical function.