The comparative effectiveness of metronidazole, furazolidone and cotrimoxazole in blastocystis hominis infectiont.

ABSTRACT

A study of the treatment of symptomatic Blastocystis hominis infection was carried out in order to compare the efficacy of the use of metronidazole, furazolidone and cotrimoxazole. Fifty-eight subjects were enrolled in this and were placed in three groups at random. The cure rates of the patients who received metronidazole on days, 7, 14 and 30 after treatment were 68.4, 68.4 and 73.7 percent respectively. The cure rates of the furazolidone treatment group on days, 7, 14 and 30 after treatment were 45.0, 70.0 and 85.0 percent respectively. The cure rates for cotrimoxazole on days, 7, 14 and 30 after treatment were 57.9, 84.2 and 78.9 percent respectively. There were no statistically significant differences in the efficacy of these drugs.