New method for measuring blood volume.

ABSTRACT

Patients without nausea received a capsule of 200 mg of Sn Cl2 orally and waited for 1 hour or patients with nausea were injected intravenously with a dose of MDP-Sn (II) and waited for 10 minutes. After the waiting time, 10 ml of blood was withdrawn. Whole blood was incubated with 99mTc 200 ตCi for 30 minutes and 1 wash with normal saline was sufficient. This procedure of labeling RBC with 99mTc is much more convenient than the conventional one. We have used this method since 1979 until 1984 with 52 patients without any adverse reaction occurring. The results are satisfactory not only in accuracy and cost but also in reducing the radiation dosage to patients and operators. This report offers 3 main benefits for this procedure. First of all it can help doctors to make decisions about the priority of examination. Secondly, it can be useful for those who are looking for a good method of measuring blood volume. Finally it can be most helpful in a teaching programme.