Chromosomal abnormalities associated with mental retardation in female subjects.
Indian J Hum Genet
;
2009 Jan; 15(1): 28-31
Article
in English
| IMSEAR
| ID: sea-138867
ABSTRACT
Chromosomal abnormalities are thought to be the most common cause of mental retardation (MR). However, apart from a few selected types with typical aneuploidy, like Downs syndrome, Klinefelter syndrome, Turner syndrome, etc., the frequency of detectable chromosomal abnormalities in association with idiopathic MR is very low. In this study, we have investigated chromosomal abnormalities in female MR subjects (n = 150) by high-resolution GTG banding. Of them, 30 cases were diagnosed as Downs syndrome. Among the remaining (n = 120), chromosomal abnormalities/marked polymorphisms were detectable in only three MR cases (0.025).
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Polymorphism, Genetic
/
Female
/
Humans
/
Chromosome Aberrations
/
Chromosome Banding
/
Down Syndrome
/
Karyotype
/
Intellectual Disability
Language:
English
Journal:
Indian J Hum Genet
Year:
2009
Type:
Article
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