Triple sugar screen breath hydrogen test for sugar intolerance in children with functional abdominal symptoms.
Article
in English
| IMSEAR
| ID: sea-141375
ABSTRACT
Background Sugar intolerance and functional gastrointestinal disorders are both common in school age children. Both may present with similar complaints such as abdominal pain, diarrhea and bloating. Lactose, fructose and sucrose hydrogen breath tests are widely used to detect sugar malabsorption. Aim To determine the proportion of children with symptoms of functional gastrointestinal disorders (FGID) that have sugar intolerance as determined by using a breath hydrogen test. Methods We prospectively enrolled subjects with chronic abdominal pain, bloating and/or chronic diarrhea. All subjects underwent triple sugar screen hydrogen breath test (TSST) using the combined sugar solution. Breath hydrogen concentration ≥20 ppm above baseline was interpreted a positive test for sugar malabsorption. Results A positive hydrogen breath test consistent with sugar malabsorption was found in 5 out of 31 (16%) subjects. Three of these subjects were confirmed to have lactose malabsorption based on small bowel lactase enzyme analysis or subsequent lactose hydrogen breath test. One subject with positive TSST was diagnosed with fructose malabsorption based on dietary history; he improved on a limited fructose diet, and one was diagnosed to have gastric Crohn’s disease. Conclusion Approximately one in six children with symptoms of FGID had sugar intolerance as determined by the TSST.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Language:
English
Year:
2010
Type:
Article
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