Prevalence of high-risk human papillomavirus types 16 and 18 in healthy women with cytologically negative pap smear in Iran.
Indian J Pathol Microbiol
;
2010 Oct-Dec; 53(4): 681-685
Article
in English
| IMSEAR
| ID: sea-141786
ABSTRACT
Background:
Because human papillomavirus (HPV) is one of the causal factors in cervical cancer, understanding the epidemiology of this infection is an important step towards developing strategies for prevention. Materials andMethods:
We evaluated the prevalence of high-risk human papillomavirus Types 16 and 18 in cervical samples from 402 healthy women with normal Pap smears by testing with type-specific primers in the polymerase chain reaction. Participants were seen at two gynecological clinics affiliated to the Shiraz University of Medical Sciences in Iran.Result:
The prevalence of positive HPV findings was 5.5%; high-risk HPV human papillomavirus Type 16 prevalence was 2% and no patient harbored HPV-18. The prevalence of HPV was 4.5% in younger age group and gradually increased to 20% in the 4 th decade.Conclusion:
The prevalence of high-risk HPV was highest in the youngest women and gradually decreased with age. Overall, the prevalence of HPV in our population is low.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2010
Type:
Article
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