Morphologic evaluation of renal function using semi-quantitative method in primary nonproliferative glomerular diseases.
Indian J Pathol Microbiol
;
2011 Jan-Mar 54(1): 42-46
Article
in English
| IMSEAR
| ID: sea-141913
ABSTRACT
Context Fibrosis is universally accepted as a poor prognostic finding in renal pathology. Semi-quantitative assessment is widely used for prognostication in pathology. Aims:
We propose a semi-quantitative method to prognosticate primary nonproliferative glomerular diseases. Settings andDesign:
A semi-quantitative method based on Banff schema, 97 classification has been modified to suit the requirements. Glomerular, tubulointerstitial, and vascular compartments were scored independently, and the scores were totaled to obtain total scores. Materials andMethods:
Seventy-six renal biopsies were assessed by semi-quantitative scores and the individual compartmental and total scores were correlated with serum creatinine levels. Follow-up was available in 24 cases. StatisticalAnalysis:
Pearson correlation coefficient, two-tailed t test, to determine the P value.Results:
P values were significant for the total scores as well as individual compartments. There is a linear correlation between the scores and serum creatinine levels. A total score of ≥5 was significant.Conclusions:
The semi-quantitative scoring system based on modified Banff schema, 1997 is useful in prognosticating renal biopsies in primary nonproliferative glomerular diseases.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prognosis
/
Severity of Illness Index
/
Fibrosis
/
Humans
/
Male
/
Child
/
Child, Preschool
/
Adolescent
/
Adult
/
Young Adult
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2011
Type:
Article
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