Transfusion-induced hemoglobinopathy in patients of beta-thalassemia major.
Indian J Pathol Microbiol
;
2011 Jul-Sept 54(3): 609-611
Article
in English
| IMSEAR
| ID: sea-142058
ABSTRACT
Apparent hemoglobinopathy acquired after blood transfusion is an uncommon cause of diagnostic dilemma resulting in repeated testing and delay in the diagnosis. Out of the 1530 hemoglobin (Hb)- high-performance liquid chromatography (HPLC) performed at our hospital (May 2009 to April 2010), 3 pediatric cases of thalassemia major were detected having posttransfusion hemoglobinopathy with HbS ranging from 9.9% to 18.5%. In all three cases, there was no variant hemoglobin in earlier documented Hb-HPLC. It is important to be aware of and consider apparent transfusion-induced hemoglobinopathy in patients with unusual percentage of variant hemoglobin to avoid unnecessary treatment and counseling.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Blood Transfusion
/
Humans
/
Male
/
Hemoglobins
/
Child, Preschool
/
Chromatography, High Pressure Liquid
/
Beta-Thalassemia
/
Hemoglobinopathies
/
Infant
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2011
Type:
Article
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