Does prophylactic use of dexamethasone have a role in reducing post extubation stridor and reintubation in children.
Indian J Pediatr
;
2009 May; 76(5): 555-557
Article
in English
| IMSEAR
| ID: sea-142206
ABSTRACT
All children aged from 4 weeks to <5 year, were intubated for at least 48 hours [n=51] during 6 months. Data of the patients treated with DEX (0.5 ml/kg every 6 hours for 3 doses, beginning 6-12 hours prior to extubation) (n=30) were compared with control patients (who had not received medication) (n=21). The DEX and control groups were similar in age i.e., mean ages of DEX group were 16.85±14 months, and that of control group were 19.02 ± 19 months, mean duration of intubation and mechanical ventilation in DEX group was 5.17 ± 4.58 days, and that in control group was 3.98 ± 3.60 days. There was no significant difference between DEX and control group in the incidence of postextubation stridor [17% (5/30) vs. 10% (2/ 21); p = 0.5] and the reintubation rate [7% (2/30) vs. 10% (2/21); p = 0.7]. Our data revealed that the prophylactic use of dexamethasone in planned extubation of high risk children were not effective.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Reference Values
/
Respiration, Artificial
/
Time Factors
/
Severity of Illness Index
/
Female
/
Humans
/
Male
/
Dexamethasone
/
Case-Control Studies
/
Child, Preschool
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Language:
English
Journal:
Indian J Pediatr
Year:
2009
Type:
Article
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