Congenital langerhans cell histiocytosis with skin and lung involvement: Spontaneous regression.
Indian J Pediatr
;
2010 July; 77(7): 811-812
Article
in English
| IMSEAR
| ID: sea-142639
ABSTRACT
Congenital self-healing Langerhans cell histiocytosis (CSHLCH) is a rare type of Langerhans Cell Histiocytosis, presenting at birth or during the neonatal period with eruption of multiple, discrete red-brown papules or nodules that undergo spontaneous regression. Systemic signs are generally absent. We describe a 4-month-old infant presenting with reddish brown nodular cutaneous lesions since birth with a past history suggestive of pulmonary involvement. Skin biopsy showed a dermal infiltrate of pleomorphic histiocytes; which were CD1a and S-100 positive, consistent with the diagnosis of CSHLCH. Both pulmonary and cutaneous lesions showed spontaneous resolution.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Remission, Spontaneous
/
Respiration Disorders
/
Skin Diseases
/
Humans
/
Male
/
Histiocytosis, Langerhans-Cell
/
Hypopigmentation
/
Infant
Language:
English
Journal:
Indian J Pediatr
Year:
2010
Type:
Article
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