Study of some genetic markers in sishta karanam population, Andhra Pradesh, India.

ABSTRACT

A total of 76 individuals belonging to Sishta Karanam population, Andhra Pradesh, were tested for polymorphism in ABO and Rh (D) blood groups, two serum proteins, Haptoglobin and Ceruloplasmin, and one red cell enzyme, Glyoxalase-I. All the systems except Caeruloplasmin showed polymorphism. The frequency of AB phenotype is found to be highest in the Sishta Karanam when compared to the other caste populations of Andhra Pradesh so far studied. It was observed that the ABO system was not in Hardy-Weinberg Equillibrium. The Hp1-1 phenotype was absent in this population. The Glyoxalase-I locus showed all the 3 phenotypes.