Demographic and cytogenetic study in recurrent spontaneous aborters.

ABSTRACT

Chromosomal analysis was performed in a series of 30 women with repeated spontaneous abortions and their husbands. Out of the 30 women, one woman of age 28 years with history of spontaneous abortions was detected to be a chromosomal mosaic 46,XX/47,XXX and with corresponding sex chromatin positive picture C +ve / ++ve. She had normal phenotype and spontaneous abortions that occurred in the second/third months of pregnancy. Her husband was normal and has normal karyotype (46,XY).