Albumin and Lipid Enriched Albumin for the Critically Ill.
Article
in English
| IMSEAR
| ID: sea-143515
ABSTRACT
Albumin, the principal transporter of plasma fatty acids, binds to majority of the drugs ingested, traps oxygen radicals and has potent anti-oxidant actions. Albumin binds to its specific binding sites on vascular endothelial cells and thus, prevents endothelial apoptosis. Albumin regulates the enzyme pyruvate dehydrogenase, the flux of glucose and lactate in astrocytes, and enhances the formation of anti-inflammatory lipoxins, resolvins and protectins from docosahexaenoic acid (DHA) and other polyunsaturated fatty acids that, in turn, could limit ischemia-induced neuronal damage. This may explain the beneficial action of DHA-enriched albumin in stroke and other critical diseases. ©
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Docosahexaenoic Acids
/
Malaria, Cerebral
/
Critical Illness
/
Sepsis
/
Neuroprotective Agents
/
Albumins
Language:
English
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS