BinaxNOW® - An immunochromatographic test for the diagnosis of human influenza viruses: Comparison with viral culture and polymerase chain reaction.
Indian J Med Microbiol
;
2011 Jan-Mar; 29(1): 19-21
Article
in English
| IMSEAR
| ID: sea-143769
ABSTRACT
Purpose:
A rapid test for influenza viruses (Binax NOW® ) was evaluated. Materials andMethods:
In season-1, 35 respiratory samples were tested retrospectively; in season-2, 45 samples were tested prospectively [gold-standard viral culture in season-1, culture+ reverse transcriptase-polymerase chain reaction (RT-PCR) in season-2].Results:
Sensitivity for Binax for influenza A was 59.3 and 0% in season-1 and -2, respectively. Sensitivity was low for influenza B (33.3% in season-1, 26.1% in season-2). Samples having low viral load were more likely to have a negative Binax test. Specificity of Binax was high (100 and 94.7% with influenza A and B, respectively).Conclusion:
Sensitivity information provided in the kit insert does not always reflect post licensure performance in clinical settings.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Orthomyxoviridae
/
Reagent Kits, Diagnostic
/
Time Factors
/
Virology
/
Virus Cultivation
/
Humans
/
Immunoassay
/
Polymerase Chain Reaction
/
Sensitivity and Specificity
/
Clinical Laboratory Techniques
Type of study:
Diagnostic study
Language:
English
Journal:
Indian J Med Microbiol
Journal subject:
Microbiology
Year:
2011
Type:
Article
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