Fatal rabies despite post-exposure prophylaxis.
Indian J Med Microbiol
;
2011 Apr-June; 29(2): 178-180
Article
in English
| IMSEAR
| ID: sea-143805
ABSTRACT
Only sporadic reports of failure of post-exposure prophylaxis for rabies exist in the published literature. We are reporting such a case in a 3-year-old boy. The child had Category III dog bite on his right thigh. He presented with progressive ascending paralysis, finally developing quadriplegia and respiratory paralysis. Typical hydrophobia and aerophobia were absent. He received four doses of antirabies cell culture vaccine. He did not receive antirabies immunoglobulin. The boy succumbed on the 23 rd day of the dog bite. Diagnosis of rabies was confirmed in the laboratory by demonstration of Negri bodies, direct fluorescent antibody test and reverse transcriptase-polymerase chain reaction either on impression smear of brain or a piece of brain taken during autopsy.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rabies
/
Bites and Stings
/
Humans
/
Male
/
Rabies Vaccines
/
Child, Preschool
/
Fatal Outcome
/
Dogs
/
Post-Exposure Prophylaxis
/
Hippocampus
Language:
English
Journal:
Indian J Med Microbiol
Journal subject:
Microbiology
Year:
2011
Type:
Article
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