Relapse of kala-azar after use of multiple drugs: A case report and brief review of literature.
Indian J Med Microbiol
;
2012 Apr-June; 30(2): 227-229
Article
in English
| IMSEAR
| ID: sea-143952
ABSTRACT
We present a case of kala-azar infection that recurred in a patient after completion of the standard treatment course of miltefosine, amphotericin B-deoxycholate (short course), and amphotericin B lipid formulations. The patient was cured after continuous amphotericin B-deoxycholate administration for 4 weeks. This is a unique case of relapse following the use of three important drugs. Although amphotericin B-deoxycholate is a second line drug in Nepal, it has shown a satisfactory clinical response with continuous treatment for 4 weeks. Therefore, an extended course of amphotericin B-deoxycholate may be beneficial in patients with resistance to the standard short course and other anti-leishmania drugs.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phosphorylcholine
/
Recurrence
/
Time Factors
/
Humans
/
Male
/
Amphotericin B
/
Adult
/
Deoxycholic Acid
/
Drug Combinations
/
Leishmaniasis, Visceral
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Med Microbiol
Journal subject:
Microbiology
Year:
2012
Type:
Article
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