Trans-differentiation of iris pigmented epithelial cells of Euphlyctis cyanophlyctis tadpoles into lens in vitro.
Indian J Exp Biol
;
2010 Jan; 48(1): 17-25
Article
in English
| IMSEAR
| ID: sea-144091
ABSTRACT
Meshed pigmented iris epithelium along with neural retina of tadpoles of the frog Euphlyctis cyanophlyctis were found to undergo dedifferentiation and subsequently transdifferentiate into lens in culture medium. During lag period, depigmentation (dedifferentiation) occurred in many cells. When culture became confluent 3-4 weeks after seeding tiny lens like structures differentiated from foci of cultured pigmented iris epithelium cells. The percentage of lens formation was higher in vitamin A treated cases. The culture system appears to be a suitable for investigating the changes occurred during trans-differentiation of pigmented epithelial cells into lens.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pigment Epithelium of Eye
/
Ranidae
/
Vitamin A
/
Iris
/
Tissue Culture Techniques
/
Cell Transdifferentiation
/
Larva
/
Lens, Crystalline
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
2010
Type:
Article
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