Ketogenic diet in indian children with uncontrolled epilepsy.
Indian Pediatr
;
2009 Aug; 46(8): 669-673
Article
in English
| IMSEAR
| ID: sea-144148
ABSTRACT
Objective:
To evaluate the efficacy of the ketogenic diet in Indian children with uncontrolled epilepsy. StudyDesign:
Prospective observational study.Setting:
Hospital based. Patients 105 children (age 4 months to 18 years) with uncontrolled epilepsy enrolled in the ketogenic diet program over a period of 9 years and followed up for 25.7 ± 20.3 months (median17 months) on the ketogenic diet. Main outcomemeasures:
Reduction in seizure frequency and comparison of improvement in two main groups of epilepsies, namely epileptic encephalopathies and localization related epilepsies.Results:
Thirty seven (35%) out of 105 children dropped out of the study and 68 remained on the diet. Thirty nine (37%) achieved 100% control, 23 (22%) achieved between 90 and 99% control, 7 (6.8%) achieved between 75 and 90% control, and 16 (15.2%) achieved between 50 and 75% control. Twenty (19%) achieved less than 50% control. Epileptic encephalopathies had a better response than localization related epilepsies.Conclusion:
The Indian version of ketogenic diet used is well tolerated and efficacious in controlling difficult-to-control epilepsy in children. Epileptic encephalopathies respond better than localization related epilepsies
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Female
/
Humans
/
Male
/
Drug Resistance
/
Child
/
Incidence
/
Prevalence
/
Adolescent
/
Treatment Outcome
/
Epilepsy
Type of study:
Incidence study
/
Observational study
/
Prevalence study
/
Prognostic study
Country/Region as subject:
Asia
Language:
English
Journal:
Indian Pediatr
Year:
2009
Type:
Article
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