Eight-year experience in esophageal cancer surgery.
Indian J Cancer
;
2011 Jan-Mar; 48(1): 34-39
Article
in English
| IMSEAR
| ID: sea-144409
ABSTRACT
Aim:
Esophageal cancer remains a major and lethal health problem. In Nepal, not much has been explored about its management. The aim of this study was to conduct a retrospective review of esophageal cancer patients undergoing surgery or combined modality treatment at a cancer hospital in Nepal. Materials andMethods:
Resectable cases were treated primarily with surgery. Locally advanced cases with doubtful or obviously unresectability underwent preoperative chemo/radiation or chemoradiation followed by surgery.Results:
Among 900 patients, 103 were treated with curative intent. Mean age of patients was 54 years, and 100% of the patients presented with complaint of dysphagia. Surgery as a single modality of treatment was done in 57% of cases, and the remaining underwent combined modality treatment. Transthoracic and transhiatal approaches were used in 95% and 5% of cases, respectively. Nodal sampling, two-field (2-FD), and three-field lymphadenectomy (3-FD) were done in 18%, 59%, and 20% of cases, respectively. A majority of patients had pathological stage III disease (46.6%). In-hospitality mortality was 5%, and anastomotic leakage rate was 14%. In 87% of patients, R0 resection was achieved. Overall, 4-year survival was 20%. A R0 resection, early-stage disease and 3-FD favored the survival advantage (P < 0.05).Conclusion:
The mortality, complication, and survival results were in the acceptable range. R0 resection and radical nodal dissection should be standard practice.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Postoperative Complications
/
Time Factors
/
Aged
/
Female
/
Humans
/
Male
/
Esophageal Neoplasms
/
Survival Rate
/
Retrospective Studies
/
Follow-Up Studies
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Indian J Cancer
Year:
2011
Type:
Article
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