Olfactory bulb serotonin level modulates olfactory recognition in neonate rat.
Indian J Exp Biol
;
2010 Nov; 48(11): 1078-1082
Article
in English
| IMSEAR
| ID: sea-145065
ABSTRACT
Role of serotonin in olfactory recognition was tested by depleting the olfactory bulb serotonin during postnatal day (PND)1- 4 following administration of 5,7-dihydroxytryptamine. Significant difference in the olfactory recognition test was observed during PND5-7; control pups successfully recognized and oriented towards their mother; whereas treated pups failed to recognize their mother odour. Later on, during PND12-14, both group of pups responded equally in the recognition test. Levels of olfactory bulb serotonin were depleted (53.3%) in the treated pups on PND-8, which was restored on PND-14 with only 15% variation. Further analysis demonstrated that depletion of serotonin in olfactory bulb did not affect the normal suckling and weight gain, it only modulates olfactory recognition.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Language:
English
Journal:
Indian J Exp Biol
Year:
2010
Type:
Article
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