Therapeutic effects of proanthocyanidins on the pathogenesis of periodontitis— An overview.
Indian J Exp Biol
;
2011 Feb; 49(2): 83-93
Article
in English
| IMSEAR
| ID: sea-145101
ABSTRACT
Periodontitis is a bacterially induced chronic inflammatory disease that destroys the connective tissue and bone that support teeth. Bacteria initiates periodontitis and destruction of the alveolar bone and periodontal connective tissue is clearly observed. But, the events occuring between these two points of time remain obscure and this study focusses on these aspects. The proanthocyanidins (PC) have variable pharmacological and nutraceutical benefits including improvement of ischemic cardiovascular disease, prevention of atherosclerosis and antiarthritic, anticancer and antimicrobial activities. The benefits associated with the antioxidant activity of PC have been evaluated both in vivo and in vitro. But, reports on the ameliorative effects of PC on oral diseases and specifically on periodontitis are very few. Hence, a novel attempt is made to review the possible protective effects of PC and its mechanism of action in periodontitis and also to show whether PC could be developed as a therapeutic agent for periodontitis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Etiology study
Language:
English
Journal:
Indian J Exp Biol
Year:
2011
Type:
Article
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