A study to evaluate asbestos fiber burden in lung and pleural malignancies.
Indian J Med Sci
;
2010 July; 64(7) 315-319
Article
in English
| IMSEAR
| ID: sea-145545
ABSTRACT
Background:
There is scarcity of data on asbestos fiber burden in lung and pleural malignancies.Aim:
To evaluate asbestos fiber burden in biopsy samples of suspected lung and pleural malignancies. StudyDesign:
This was a single-centre, observational study. Study Period From August 2010 to July 2010.Setting:
Department of Pulmonary Medicine, CSMMU, UP, Lucknow, a tertiary care hospital in India. Study Population Suspected cases of lung and pleural malignancy. Materials andMethods:
Biopsy tissues taken by computed tomography (CT)-guided biopsy, bronchoscopic biopsy, and pleural biopsy by Cope's needle were analyzed for histopathology and asbestos burden by Haq et al.'s method.Results:
20 patients were studied. Mean fiber burden was 9.25 × 10 4 fibers/g. Average burden in lung malignancies (11 patients) was 9.178 × 10 4 fibers/g and in pleural tissue (9 patients) was 9.332 × 10 4fibers/g. Among the different cell types, mean fiber burden in squamous cell carcinoma was 8.99 × 10 4 fibers/g, in adenocarcinoma was 9.71 × 10 4 fibers/g, and in small cell carcinoma was 7.54 × 10 4 fibers/g. Mean fiber burden in bronchoscopic endobronchial biopsy tissue was 10.69 × 10 4 fibers/g, while in CT-guided biopsy was 8.60× 10 4fibers/g.Conclusion:
Maximum number of fibers was found in adenocarcinoma.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Patients
/
Pleural Neoplasms
/
Asbestos
/
Biopsy
/
Humans
/
Adenocarcinoma
/
Tomography, X-Ray Computed
/
Image-Guided Biopsy
/
Tertiary Care Centers
/
India
Type of study:
Observational study
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Med Sci
Year:
2010
Type:
Article
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