Sublingual misoprostol: A better choice for cervical priming before manual vacuum aspiration.
Indian J Med Sci
;
2010 Aug; 64(8) 356-362
Article
in English
| IMSEAR
| ID: sea-145553
ABSTRACT
Background:
Misoprostol is effective for cervical priming before manual vacuum aspiration (MVA). Aim of study was to determine whether sublingual misoprostol with a shorter interval of 2 hours before MVA would be as effective as its standard vaginal administration. StudyDesign:
This randomized control trial included 82 women randomly assigned to receive 400 mcg of misoprostol, either sublingually or vaginally. MVA was performed 2 hours and 3 hours after in sublingual and vaginal group, respectively.Results:
Cervical dilatation of 8 mm was achieved within 2 hours in sublingual group. Mean time taken for procedure (14.4 ± 5.3 sublingual group and 16.2 ± 5.7 vaginal group), and blood loss was comparable (12.2 ± 9.7 ml in sublingual group and 13.7 ± 8.5 ml in vaginal group).Conclusion:
2 hour of cervical priming with 400 mcg of sublingual misoprostol before MVA was as good as 3 hours with vaginal administration of the same dose.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Vacuum Curettage
/
Administration, Intravaginal
/
Preoperative Care
/
Female
/
Humans
/
Administration, Sublingual
/
Cervix Uteri
/
Drug Administration Routes
/
Blood Loss, Surgical
/
Misoprostol
Type of study:
Controlled clinical trial
Language:
English
Journal:
Indian J Med Sci
Year:
2010
Type:
Article
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