Pharmacological efficacy of argemone mexicana plant extract, against cysteamine-induced duodenal ulceration in rats.
Indian J Med Sci
;
2011 Mar; 65(3) 92-99
Article
in English
| IMSEAR
| ID: sea-145596
ABSTRACT
Objective:
The plant Argemone mexicana is traditionally used as diuretic, anti-inflammatory, antibacterial, antifungal agent, and has wound-healing property. This study was carried out to evaluate the effect of A. mexicana aerial part of the plant (methanolic and aqueous extract p.o.) on duodenal ulceration. Materials andMethods:
The study was carried out on the duodenal ulceration model by using cysteamine hydrochloride. Ranitidine (20 mg/kg) was used as standard drug.Results:
Both the extracts of the plant A. mexicana produced a significant activity in cysteamine-induced duodenal ulceration. The aqueous extract at the dose-dependent manner showed the potent activity than methanolic extract.Conclusion:
The plant A. mexicana Linn. Increased healing of gastric ulceration and prevented the development of experimentally induced duodenal ulceration in rats.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Ranitidine
/
Plant Extracts
/
Rats, Wistar
/
Cysteamine
/
Argemone
/
Disease Models, Animal
/
Duodenal Ulcer
/
Animals
/
Mice
Country/Region as subject:
Mexico
Language:
English
Journal:
Indian J Med Sci
Year:
2011
Type:
Article
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