Analytical calculation and acid-base analysis for detection of mixed disorders in critical care medicine.
Article
in English
| IMSEAR
| ID: sea-145700
ABSTRACT
Aim:
The purpose of the study was to validate the systematic six-step arterial blood gas (ABG) analysis in critically ill patients to diagnose mixed ABG disorders. Materials andmethod:
The study was conducted in the ICU of a tertiary care hospital (between 1 June and 30 September, 2007) for 4 months. A total of 560 ABG samples were evaluated from 183 patients. 50 samples were randomly picked and evaluated by single step, quick look method and six-step approaches for detecting mixed ABG disorders.Results:
Single, quick and six-step methods when applied on same data, revealed higher number of mixed disorders with systematic six-step approach. Quick-step method revealed only 48% mixed disorders while six-step analysis confirmed 62% having mixed disorders, from the samples which initially appeared to be single disorder. Metabolic acidosis with respiratory acidosis (26%) was the commonest disorder. Metabolic acidosis with respiratory alkalosis (20%), respiratory alkalosis with metabolic alkalosis (6%), metabolic alkalosis with respiratory acidosis (4%), metabolic acidosis with NGMA (4%) and metabolic acidosis with metabolic alkalosis (2%) were the other mixed disorders seen.Conclusion:
Mixed disorders as suspected on clinical grounds can only be validated after complete analysis by six-step approach in critically ill patients. pH, PaCO2, and HCO3 – allow determination of primary disorder, but it is only the inequality between predicted and actual compensatory response for simple acid-base disorders which reveals a mixed disorder.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Acid-Base Equilibrium
/
Acidosis
/
Acidosis, Respiratory
/
Humans
/
Sampling Studies
/
Critical Illness
/
Critical Care
/
Alkalosis
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Alkalosis, Respiratory
/
Tertiary Care Centers
Type of study:
Diagnostic study
/
Prognostic study
Language:
English
Year:
2012
Type:
Article
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