Comparison of some salivary characteristics between children with and without early childhood caries.
Article
in English
| IMSEAR
| ID: sea-145795
ABSTRACT
Background and Aim:
Early childhood caries (ECC) is one of the most common chronic childhood diseases. Saliva as a host factor plays an essential role in maintaining the integrity of oral structures. The aim of the present study was to compare resting salivary pH, buffering capacity, and secretory immunoglobulin A (sIgA), calcium, and phosphate concentrations between children with and without ECC. Materials andMethods:
In this cross-sectional study, samples of unstimulated saliva of 90 children (45 in ECC group and 45 in caries-free group) were taken with Scully method. The pH and buffering capacity were determined by pH meter. sIgA, calcium, and phosphate concentrations were quantitated with ELISA, CPC photometric, and phosphomolybdate/UV methods.Results:
The mean resting salivary pH was significantly higher among children without ECC and the buffering capacity was significantly better among this group (P = 0.002). The mean sIgA concentration was significantly higher among the ECC group (P = 0.015). There were no statistically significant differences between calcium and phosphate concentrations between the two groups.Conclusion:
The higher mean resting salivary pH and better buffering capacity found in children without ECC are probably the contributing factors that protect against caries development; but further studies are needed to understand the effects of saliva and its characteristics and components on ECC.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phosphates
/
Saliva
/
Buffers
/
Humans
/
Immunoglobulin A, Secretory
/
Enzyme-Linked Immunosorbent Assay
/
Child, Preschool
/
Calcium
/
Dental Caries
/
Hydrogen-Ion Concentration
Type of study:
Observational study
Language:
English
Year:
2012
Type:
Article
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