Estimation of annual risk of tuberculosis infection among children irrespective of BCG scar in the south zone of India.

ABSTRACT

Objective: To estimate the proportion infected and compute Annual Risk of Tuberculosis Infection (ARTI) among children irrespective of BCG scar and compare with that among children without BCG scar. Methodology: Tuberculin survey was conducted in south zone of India as a part of the nation-wide survey to estimate the ARTI in different parts of the country and ARTI was computed among children without BCG scar excluding children with BCG scar. In this exercise, the tuberculin test results of children with BCG scar and irrespective of BCG scar were considered for analysis and the results were compared. Results: The prevalence of infection and ARTI estimated among children irrespective of BCG scar aged 1-9 years were 5.7% and 1.0% (95% C.I 0.8-1.3) respectively. The corresponding figures among unvaccinated children were 5.9% and 1.0% (95% C.I 0.7-1.4) respectively. The ARTI among children irrespective of BCG scar were similar to that among unvaccinated children. Conclusion: Estimation of proportion of children infected and computation of ARTI using mirror-image technique could be undertaken among children irrespective of BCG scar among children aged either from 1-9 years or 5-9 years.