Acute Respiratory Distress Syndrome as a paradoxical response to anti-tuberculosis and anti-retroviral therapy.
Article
in English
| IMSEAR
| ID: sea-146926
ABSTRACT
Paradoxical response or immune reconstitution inflammatory syndrome (IRIS) during the course of antituberculous therapy is being increasingly recognised among patients with and without HIV co-infection. A 40-year-old HIV infected male on anti-retroviral therapy (ART) presented with persistent fever and weight loss. He was diagnosed to have miliary tuberculosis and HIV co-infection. Following initiation of anti-tuberculous chemotherapy, the clinical course was characterised by development of acute respiratory failure (ARDS) as a paradoxical response/IRIS to treatment. This uncommon manifestation of paradoxical response (ARDS) in HIV and tuberculous co-infection following initiation of ART and anti-TB treatment is very scarcely reported in the past. With the increasing incidence of HIV/AIDS and TB co-infection along with liberal access to ART in the developing world, it is likely that paradoxical reactions will be encountered more frequently.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Language:
English
Year:
2006
Type:
Article
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