Effect of Vanillin on lipid profile in a model of hyperlipidemia, a preliminary study.
Indian J Exp Biol
;
2013 Apr; 51(4): 288-291
Article
in English
| IMSEAR
| ID: sea-147594
ABSTRACT
To evaluate the effect of vanillin on the lipid profile of high fat diet induced hyperlipidemia in rats, the hyperlipidemia was induced by feeding cholesterol-rich high fat diet for 45 days in wistar rats of either sex. The reduction in the triglycerides and VLDL-C was significant at 200 & 400 mg/kg dose of vanillin compared to atorvastatin group. Reduction in total cholesterol was significant at 200 and 400 mg/kg doses compared to hyperlipidemic control. The results demonstrate that vanillin at a dose of 200 and 400 mg/kg body weight lowers the serum triglyceride, VLDL-C and total cholesterol level significantly in high fat diet induced hyperlipidemic rats. However there was no significant effect on the lipid profile at 100 mg/kg dose. There were no statistically significant changes in the HDL-C and LDL-C levels at any of the given doses.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Oxygen
/
Pyrroles
/
Rats
/
Triglycerides
/
Benzaldehydes
/
Female
/
Male
/
Dietary Fats
/
Gene Expression Regulation
/
Cholesterol
Language:
English
Journal:
Indian J Exp Biol
Year:
2013
Type:
Article
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