Analysis of cytotoxic potential of the aqueous leaf extracts of pogostemon Auricularius (l.) Hassk. using Allium cepa root tip assay.
Article
in English
| IMSEAR
| ID: sea-148282
ABSTRACT
Pogostemon auricularius is an aromatic herb belonging to the family Lamiaceae. Objectives:
In the present study we have utilized the Allium cepa root tip meristem model to evaluate the cytotoxic and antimitotic potential of P. auricularius.Methods:
The roots of Allium cepa were exposed to different concentrations of the aqueous leaf extracts (0.01%, 0.05%, 0.1% and 0.5%), for four different time durations, using distilled water as the control.Results:
Chromosome anomalies including formation of sticky chromosomes, chromosome bridges and several other metaphasic and anaphasic disorders were induced by all the extract concentrations.Conclusions:
Mitotic index was found to be decreasing, which was concentration dependent. All the extracts induced lowering of the mitotic index when compared to the distilled water control.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Language:
English
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS