Molecular Docking Study on Dipeptidyl Peptidase-4 Inhibitors.
Article
in English
| IMSEAR
| ID: sea-148290
ABSTRACT
Dipeptidyl peptidase (DPP)-IV inhibitors are a new approach to the treatment of type 2 diabetes. DPP-IV is a member of a family of serine peptidases that includes quiescent cell proline dipeptidase (QPP), DPP8, and DPP9. DPP-IV is a key regulator of incretin hormones, but the functions of other family members are unknown. To determine the importance of selective DPP-IV inhibition for the treatment of diabetes, we conducted molecular docking studies on clinical inhibitors of DPP-IV.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Language:
English
Year:
2013
Type:
Article
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