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Molecular Docking Study on Dipeptidyl Peptidase-4 Inhibitors.
Article in English | IMSEAR | ID: sea-148290
ABSTRACT
Dipeptidyl peptidase (DPP)-IV inhibitors are a new approach to the treatment of type 2 diabetes. DPP-IV is a member of a family of serine peptidases that includes quiescent cell proline dipeptidase (QPP), DPP8, and DPP9. DPP-IV is a key regulator of incretin hormones, but the functions of other family members are unknown. To determine the importance of selective DPP-IV inhibition for the treatment of diabetes, we conducted molecular docking studies on clinical inhibitors of DPP-IV.

Full text: Available Index: IMSEAR (South-East Asia) Language: English Year: 2013 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Language: English Year: 2013 Type: Article