Structure activity relationship studies of synthesised pyrazolone derivatives of imidazole, benzimidazole and benztriazole moiety for anti-inflammatory activity.
Article
in English
| IMSEAR
| ID: sea-150797
ABSTRACT
In the present investigation, a series of some synthesis and biological evaluation of some pyrazolone derivatives with imidazole, benzimidazole and benztriazole moiety were synthesized and tested for their anti-inflammatory activity in-vitro using celecoxib as a reference drug. Compound 8d was found to be the most potent derivative of the series with 75 %inhibition of inflammation.
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Index:
IMSEAR (South-East Asia)
Language:
English
Year:
2011
Type:
Article
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